Dysplastic nevus - Dysplastesche Nevus
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An den 2022 Stiftung Warentest Resultater aus Däitschland war d'Zefriddenheet vum Konsument mam ModelDerm nëmme liicht manner wéi mat bezuelte Telemedizin Konsultatiounen.
Dysplastic nevi – eng Biopsie gëtt fir d'Westerner recommandéiert.
relevance score : -100.0%
ReferencesDysplastic nevus, och bekannt als atypesch oder Clark's nevus, huet Debatten an der Dermatologie an der Dermatopathologie ausgeléist. Dokteren maachen dacks eng Biopsie vun dësen Mole, well se anormal ausgesinn an d'Bedenken iwwert e Melanom erhéijen.
A dysplastic nevus is also referred to as an atypical or Clarks nevus and has been the topic of much debate in the fields of dermatology and dermatopathology. It is an acquired mole demonstrating a unique clinical and histopathologic appearance that sets it apart from the common nevus. These moles appear atypical clinically, often with a fried-egg appearance, and are commonly biopsied by providers due to the concern for melanoma.
A dysplastic nevus is also referred to as an atypical or Clarks nevus and has been the topic of much debate in the fields of dermatology and dermatopathology. It is an acquired mole demonstrating a unique clinical and histopathologic appearance that sets it apart from the common nevus. These moles appear atypical clinically, often with a fried-egg appearance, and are commonly biopsied by providers due to the concern for melanoma.
Dysplastic nevi, och bekannt als atypisch oder Clark‑Nevi, kann heiansdo zu Melanom féieren. Ongeféier 36 % vun de Melanome gi bei dysplastesche Nevi fonnt. Zeechen, datt en dysplastesche Nevus zu Melanom verwandelt, enthalen ongläich Form, méi Pigmentännerungen oder eng gréisser Faarf. Dës Kanceren geschéien normalerweis an engem méi jonken Alter (rond d'Mëtt vun den Drëssegjärege), kënne multiple sinn a sinn dacks um Stamm. Genetesch si dysplastic nevi tëscht benign Nevi a Melanom. Allerdéngs kommen nëmmen 20 % bis 30 % vun de Melanome aus existéierenden Nevi. Well déi meescht Nevi kee Melanom ginn, ass et normalerweis net recommandéiert, se präventiv ze läschen.
Dysplastic nevus, also called atypical or Clark nevus, can be precursor to melanoma, as the observation that 36% of melanomas have dysplastic nevi near the invasive tumor supports. Signs that a dysplastic nevus may have transitioned into a melanoma include asymmetry in contour, a noticeable increase in pigment variations, or a grayish tint indicating regression. These malignancies typically arise at a younger age (mid-thirties), are sometimes multiple, and are often found on the trunk. Molecularly, dysplastic nevi have a profile intermediate between benign nevi and malignant melanoma. While there is a recognized connection between dysplastic nevi and melanoma, it’s crucial to note that only about 20% to 30% of melanomas evolve from preexisting nevi. Given that the majority of dysplastic and typical nevi do not develop into melanoma, preventive removal of melanocytic nevi is not typically advised.
Dysplastic nevus, also called atypical or Clark nevus, can be precursor to melanoma, as the observation that 36% of melanomas have dysplastic nevi near the invasive tumor supports. Signs that a dysplastic nevus may have transitioned into a melanoma include asymmetry in contour, a noticeable increase in pigment variations, or a grayish tint indicating regression. These malignancies typically arise at a younger age (mid-thirties), are sometimes multiple, and are often found on the trunk. Molecularly, dysplastic nevi have a profile intermediate between benign nevi and malignant melanoma. While there is a recognized connection between dysplastic nevi and melanoma, it’s crucial to note that only about 20% to 30% of melanomas evolve from preexisting nevi. Given that the majority of dysplastic and typical nevi do not develop into melanoma, preventive removal of melanocytic nevi is not typically advised.
E Melanom ass eng Zort Tumor, déi sech formt, wann Melanocyten – Zellen, déi fir d’Hautfaarf verantwortlech sinn – anormal ginn. Melanozyten entstinn aus dem neuralen Kamm. Dëst bedeit, datt Melanome sech net nëmmen op der Haut entwéckelen kënnen, mee och an anere Beräicher, wou neural Kammzellen migréieren, wéi de Magen‑Darmtrakt a Gehir. D’Iwwerliewensquote fir Patientë mat fréizäitegem Melanom (Stage 0) ass héich – ronn 97 % –, wärend se fir déi mat fortgeschrattem Stadium (Stage IV) nëmmen ongeféier 10 % beträgt.
A melanoma is a tumor produced by the malignant transformation of melanocytes. Melanocytes are derived from the neural crest; consequently, melanomas, although they usually occur on the skin, can arise in other locations where neural crest cells migrate, such as the gastrointestinal tract and brain. The five-year relative survival rate for patients with stage 0 melanoma is 97%, compared with about 10% for those with stage IV disease.
A melanoma is a tumor produced by the malignant transformation of melanocytes. Melanocytes are derived from the neural crest; consequently, melanomas, although they usually occur on the skin, can arise in other locations where neural crest cells migrate, such as the gastrointestinal tract and brain. The five-year relative survival rate for patients with stage 0 melanoma is 97%, compared with about 10% for those with stage IV disease.
○ Kriibsrisiko
Wéi bei kausales Individuen an den USA gesi gëtt, hunn déi mat dysplastesche Nevi e Risiko fir Melanom vu méi wéi 10 % ze entwéckelen. Op der anerer Säit hunn déi ouni dysplastesche Nevi e Risiko fir Melanom vu manner wéi 1 % ze entwéckelen.
○ Precautioun fir Individuen mat dysplasteschen Nevi
Eng Hautselbstuntersuchung gëtt normalerweis recommandéiert, fir Melanom ze vermeiden (duerch d'Identifikatioun vun atypeschen Nevi, déi ewechgeholl kënne ginn) oder fir fréizäiteg Detektioun vun existente Tumoren. Leit mat enger perséinlecher oder familiärer Geschicht vu Hautkriibs oder vu multiplen atypeschen Nevi sollten op d'mannst eemol d'Joer en Dermatolog gesinn, fir sécher ze sinn, datt se kee Melanom entwéckelen.
D'Ofkierzung [ABCDE] war nëtzlech fir Gesondheetsversuergers a Laien ze hëllefen, d'Schlësselcharakteristiken vun engem Melanom z'erënneren. Leider kënnen vill seborrheesch Keratosen, e puer lentigo senilis a souguer Warzen [ABCDE]-Charakteristiken weisen, déi net vun engem Melanom ënnerscheedbar sinn.
○ [ABCDE]
Asymmetriesch: Asymmetresch Läsion.
Border: D'Grenz vun der Läsion ass onregelméisseg.
Color: Melanome hunn normalerweis méi onregelméisseg Faarwen.
Diameter: Nevi, déi méi wéi 6 mm Duerchmiesser hunn, sinn wahrscheinlech méi melanoomhaft wéi méi kleng Nevi.
Evolution: D'Evolutioun (dh. Ännerung) vun engem Nevus oder Läsion kann weisen, datt d'Läsion bösarteg gëtt.